A groundbreaking study conducted by Michigan State University (MSU) has revealed that non-deceptive placebos—those given to participants with full knowledge that they are placebos—can effectively manage stress, anxiety, and depression. This discovery is particularly notable as the study demonstrated these effects even when the placebos were administered remotely.
The research team recruited individuals experiencing prolonged stress due to the COVID-19 pandemic for a two-week randomized controlled trial. Participants were divided into two groups: one received non-deceptive placebos, while the other served as a control group with no treatment. The participants engaged in four virtual sessions via Zoom, during which those in the placebo group were educated about the placebo effect and provided with placebo pills sent by mail, along with instructions on their use.
The study, published in the journal Applied Psychology: Health and Well-Being, found that the group receiving non-deceptive placebos experienced a significant reduction in stress, anxiety, and depression within just two weeks, compared to the control group. Additionally, participants reported that the placebos were easy to use, non-burdensome, and suitable for the situation.
“Long-term stress can severely impair emotional regulation and lead to serious mental health issues. We’re excited to find that an intervention requiring minimal effort can yield such substantial benefits,” said Jason Moser, co-author of the study and professor in MSU’s Department of Psychology. “The minimal burden associated with non-deceptive placebos makes them an appealing option for individuals dealing with significant stress, anxiety, and depression.”
The researchers emphasized the potential of remotely administered non-deceptive placebos to broaden access to mental health interventions, particularly for those who may not have access to traditional mental health services.
“This ability to administer non-deceptive placebos remotely significantly enhances their scalability,” added Darwin Guevarra, co-author of the study and postdoctoral scholar at the University of California, San Francisco. “These remotely administered placebos could be a valuable tool for individuals struggling with mental health concerns, offering them a viable alternative when traditional services are inaccessible.”
The findings highlight a promising new avenue for mental health care, suggesting that even the knowledge of taking a placebo can lead to real, measurable improvements in emotional well-being.